przez Woodson1995 » piątek, 2 wrz 2016, 18:39
IMO tak - są metabolizowane do właściwych hormonów w watrobie, tak dla ciekawych:
Do they have side effects?
Yes. Prohormones can have the same side effects as anabolic steroids, and arę dependant upon the user as to which side effects one might experience. somę side effects arę acne, hair loss, breast tissue enlargement, and prostatę swelling. The potential for these side effects does exist, but it can be reduced if one uses proper precautionary measures (see below). Generally, if a person is genetically predisposed to a side effect it will occur (i.e.: if someone has a history of male pattern baldness in the family, it could be assumed that this could be a side effect experienced if certain prohormones arę used)
Which prohormones convert to which compounds?
Here is a list
4 androstenediol (4AD or 4diol) converts to testosterone
19 nor-4-androstenediol (Nordiol) converts to nortestosterone or nandrolone
1 androstenediol (1AD) converts to 1-testosterone (dihydroboldenone)
1,4 androstenedione and 1,4 androstenediol (1,4andro or Boldione) converts to boldenone and slightly converts to estrogen (the diol version does not convert to estrogen)
5 alpha androstenediol (5AA) converts to DHT
3 beta androstenediol (3 beta) converts to DHT
3 alpha androstenediol (3 alpha) converts to DHT
4 hydroxy androstenedione converts to 4 hydroxy testosterone which is Ań aromatize inhibitor (blocks formation of estrogen)
7-KETO-DHEA does not convert to any active anabolic compounds
1-testosterone (1-test) is already Ań active compound and does not need to undergo conversion
Compounds you want to avoid.
5 androstenediol (5AD or 5diol) converts to testosterone at a very low ratę and is Ań estrogen agonist
4 androstenedione (andro) converts to testosterone and estrone (estrogen)
19 nor-4-androstenedione (norandro) converts to nortestosterone and estrogen
DHEA converts to androstenedione and can be converted to all other hormones
Pregnenolone converts to progesterone and can be converted to all other hormones
How do prohormones work?
Basically, when they arę administered into the system, they arę broken down in the liver and converted to their target hormone via certain enzymes. There have been a number of quotes describing how much of the hormone is converted, but there is no definitive answer as to how much of the prohormone is converted into its target active. Once a certain amount is created, the enzymes used for conversion become saturated and no morę can be converted. This is true with all the compounds, except for 1-testosterone which really isn’t a prohormone.
How can I avoid somę of the potential side effects associated with prohormones?
There arę certain ancillary compounds available to treat potential side effects of prohormones. Below is a list I compiled which is pretty basic and should help clarify somę of the issues of side effects.
prostatę Issues
The prostatę is Ań organ at the neck of the bladder where it joins the urethra. It is responsible for controlling urination and ejaculation. Common symptoms of prostatę problems arę frequent or difficult urination, dribbling when urinating, erection difficulty, and pain in that generał area. Either a rise in estrogen or DHT levels from increased testosterone, etc., probably causes this. If you have ongoing prostatę issues, it’s best not to use prohormones, though potentially the use of nordiol might be acceptable.
Herbal treatments:
Saw Palmetto Extract – Usual dosage is 160mg several times daily
Beta sisterol or plant phytosterols – 300mg several times daily
Flax seed oil – anywhere from 5-2 tblspoons daily
Prescription Treatments:
Proscar/Propecia – blocks the conversion of testosterone to DHT. Ineffective with DHT derived hormones (1-test, 1ad, 5aa, etc)
Spironolactone – Ań anti androgen. Best not used for this, but used topically (more below)
Acne
Acne is very common on prohormone cycles, and can rangę from mild to moderate. It will go away once post cycle treatment concludes, or within a few weeks of cession of the product. The best way to treat acne is with the soaps available at your local grocery storę or pharmacy. Just pick up somę Neutrogena or whatever and scrub your face twice a day or use the body wash.
Hair Loss
Hair loss is caused by increased levels of DHT. sińce DHT receptors arę heavy on the top of the scalp, somę people will notice a lot of shedding or a receding hairline on somę cycles. There arę various treatments for this; the most common is topical Spironolactone available from Nizoralman or Dr. Lee. The 2% will work as a preventative measure, while the 5% will attempt to help grow somę hair back. There arę also other methods, such as azelaic acid or Nizoral shampoo, but they arę not proven to be effective as spiro is.
If you arę concerned you arę losing your hair and arę currently taking something to help prevent it, prohormones arę probably not the best idea. If still interested in using prohormones, Nordiol might be the best option available to you.
Gyno
Gynocomastia, or development of the breast tissue, is sometimes common among aromatizing (converting to estrogen) prohormones. The first symptoms arę puffy and itchy or swollen nipples. If you start to notice this while on a cycle, you need to start taking Nolvadex immediately. Formasin/Aromazap/Formastat might work, but 6oxo is not going to help this in most cases, so Nolvadex should ALWAYS be on hand for this situation. It is highly available, not very expensive, and not illegal to posses, so there is no reason not to have it. Don’t wait and order somę when you start to get the first signs of gyno, because Nolvadex needs to be taken as soon as symptoms of gyno appear. Start taking 40mg a day until the symptoms subside, and you may want to continue to takę 10mg the rest of your cycle as precaution.
Liver/Kidney
Prohormones have to pass through your liver in order to convert, no matter what the route of administration, so higher levels of liver enzymes in the blood is common during a cycle. Many steroid users takę Milk Thistle and ALA at high doses to combat this, and if you arę concerned it would be a good idea to takę one or both of these to help that. Problems with kidneys have not been Ań issue to my knowledge, but steroid users will often also takę cranberry juice extract to help with that.
Depression
somę people report mild or moderate depression, especially post cycle when using 6oxo. This can be cured with prescription drugs such as Zoloft, IPaczoI, Paxil, etc. It can also be fought with herbal supplements such as St Johns Wort, 5-HTP or Sam-E. If you go with the herbal route, St Johns Wort should be 300mg 2-3 times daily, 5-HTP at 100mg several times daily, or 100-200mg of Sam-E once daily. You can combine all three if depression is extreme, otherwise my pick would be St. Johns Wort.
Testicular Atrophy
Many users report testicular shrinkage during a cycle. The testes will come back to full size once you start post cycle. If they do not, then it’s recommended you takę Clomid and possibly even HCG to help restore them.
Sleeplessness
somę people report having trouble falling asleep or staying asleep on a cycle. My recommendation is to takę 1mg to 3mg of melatonin 3 minutes before bed time. somę other options arę Valerian root, GABA, Tylenol PM or Kava Kava (potentially stressful on the liver).
