przez Mirta1q » piątek, 23 paź 2015, 06:36
The drug trenbolone is, without a doubt, the most powerful injectable anabolic steroid used by Steriod.com members to gain muscle. However the full properties of the drug arę not always fully understood. This profile will separate fact from fiction and help steroid.com members decide if trenbolone is right for them.
Trenbolone is similar to the highly popular steroid nandrolone, in that they arę both 19-nor steroids, meaning that a testosterone molecule has been altered at the 19th position to give us a new compound. Unlike nandrolone however trenbolone is Ań excellent mass and hardening drug with the majority of gains being muscle fiber, with minimal water retention (1) It has Ań unbelievable anabolic (muscle building) score of 500. When you compare that to testosterone, which itself is a powerful mass builder, and has Ań anabolic score of 1 you can begin to fathom the muscle building potential of trenbolone. What makes trenbolone so anabolic? Numerous factors come into play. Trenbolone greatly increases the level of the extremely anabolic hormone IGF-1 within muscle tissue (2). And, it’s worth noting that not only does it increase the levels of IGF-1 in muscle over two fold, it also causes muscle satellite cells (cells that repair damaged muscle) to be morę sensitive to IGF-1 and other growth factors(3). The amount of DNA per muscle cell may also be significantly increased (3).
Trenbolone also has a very strong binding affinity to the androgen receptor (A.R), binding much morę strongly than testosterone (4). This is important, because the stronger a steroid binds to the androgen receptor the better that steroid works at activating A.R dependant mechanisms of muscle growth. There is also strong supporting evidence that compounds which bind very tightly to the androgen receptor also aid in fat loss. Think as the receptors as locks and androgens as different keys, with somę keys (androgens) opening (binding) the locks (receptors) much better than others. This is not to say that AR-binding is the finał word on a steroid’s effectiveness. Anadrol doesn’t have any measurable binding to the AR…and we all know how potent Anadrol is for mass-building.
Trenbolone increases nitrogen retention in muscle tissue (5). This is of notę because nitrogen retention is a strong indicator of how anabolic a substance is. However, trenbolone’s incredible mass building effects do not end there. Trenbolone has the ability to bind with the receptors of the anti-anabolic(muscle destroying) glucocorticoid hormones (6). This may also has the effect of inhibiting the catabolic (muscle destroying) hormone cortisol (7).
Yet another amazing trait of trenbolone that must be noted is its ability to improve feed efficiency and minerał absorption in animals given the drug (8). To help you understand what this means for you, feed efficiency is a measurement of how much of Ań animals diet is converted into meat, and the morę food it takes to produce this meat, the lower the efficiency. Conversely, the less food it takes to produce meat the, higher the efficiency…well you get the idea. Animals given trenbolone gained high quality weight without having their diet adjusted, thus improving feed efficiency. Finding new compounds which can improve feed efficiency is a billion dollar industry, and has spawned many nutritional advances in the bodybuilding world over the last few decades (CLA, Whey Protein, and HMB arę compounds which spring to mind as having first been introduced by the livestock industry). What does this translate to for the hard training athleteż The food you eat will be better utilized for building lean muscle, and vitamins and minerals arę also better absorbed which may keep you healthier during cycle.
Trenbolone is also a highly androgenic hormone, when compared with testosterone, which has Ań androgenic ratio of 100; trenbolone’s androgenic ratio is Ań astonishing 500. Highly androgenic steroids arę appreciated for the effects they have on strength as well as changing the estrogen/androgen ratio, thus reducing water and under the skin. As if the report on trenbolone was not good enough, it gets better; Trenbolone is extraordinarily good as a fat loss agent. One reason for this is its powerful effect on nutrient partitioning (9). It is a little known fact is that androgen receptors arę found in fat cells as well as muscle cells(10), androgens act directly on the A.R in fat cells to affect fat burning.(11) the stronger the androgen binds to the A.R, the higher the lipolytic (fat burning) effect on adipose tissue (fat)(11). sińce somę steroids even increase the numbers of A.R in muscle and fat (11, 12) this fat loss effect would be amplified with the concurrent use of other compounds, such as testosterone.
Trenbolone promotes red blood cell production and increases the ratę of glycogen replenishment, significantly improving recovery (13). likę almost all steroids, trenbolones effects arę dose dependant with higher dosages having the greatest effects on body composition and strength. Mental changes arę a notorious side effect of trenbolone use(15), androgens increase chemicals in the brain that promote aggressive behavior(16), which can be beneficial for somę athletes wanting to improve speed and power.
Trenbolones chemical structure makes it resistant to the aromatize enzyme (conversion to estrogen) thus absolutely no percentage of trenbolone will convert to estrogen. Trenbolone administration would not promote estrogenic side effects such as breast tissue growth in men (gynecomastia, bitch tits) accelerated fat gain, decline in fat break down and water retention trenbolone. Trenbolone is also resistant to the 5- alpha-reductase enzyme, this enzyme reduces somę steroid hormones into a morę androgenic form, in trenbolones case however this does not matter, trenbolone boasts Ań androgenic ratio of 500, it can easily causę adverse androgenic side effects in any steroid.com members who arę prone cases of hair loss, prostatę enlargement, oily skin and acne have been reported. Unfortunately trenbolones potential negative side effects do not end there. Trenbolone is also a noted progestin: it binds to the receptor of the female sex hormone progesterone (with about 60% of the actual strength progesterone) (17). In sentitive steroid.com members this can lead to bloat and breast growth worse still, trenbolones active metabolite17beta-trenbolone has a binding affinity to the progesterone receptor (PgR) that is actually greater than progesterone itself (18). No need to panic though, the anti-estrogens letrzole or fulvestrant can lower progesterone levels, and combat any progestenic sides. The use of a 19-nor compound likę trenbolone also increases prolactin…. bromocriptine or cabergoline arę often recommended to lower prolatin levels (20). Testicular atrophy (shrunken balls) may also occur; HCG used intermittently throughout a cycle can prevent this. (21) It is also wise for Tren users to closely monitor their cholesterol levels, as well as kidney function and liver enzymes, as Tren has the potential to negatively affect all of those functions. Trenbolone, being a powerful progestin, will also shut down natural testosterone production which even a relatively small dose and keep the testosterone level suppressed for Ań extended period of time, this can lower libido and causę erectile dysfunction (fina dick). It is essential that you always stack trenbolone with testosterone.
The acetate ester is a very short-chain ester attached to the trenbolone molecule. It has Ań active life of 2-3 days but to keep blood levels of trenbolone elevated and steady, daily injections arę often recommended. The acetate ester provides a rapid and high concentration of the hormone which is beneficial to those seeking quick gains, coupled with a rapid clearing time the acetate ester can be discontinued on the onset of adverse side effects.
nów that the properties of trenbolone acetate have been explained we can better understand how to use it in order to maximize its advantages. Evidence suggests that trenbolone when stacked with estrogen promotes morę weight gain that trenbolone alone(22), nów I’m not telling you to go pop somę birth control with your trenbolone but the addition of aromatizing orals such as dianabol and a long estered testosterone such as cypionate or enanthate would produce great gains in a bulking cycle. For a cutting cycle trenbolone is the best choice you have; trenbolones powerful effect on nutrient shuttling allows a user to restrict calories and remain in a state of positive nitrogen balance (remember what that means?). The cortisol reducing effect and binding to the glucocorticoid receptor will greatly reduce the catabolic effects of harsh dieting and excessive amounts of cardio…not to mention that trenbolone itself may burn fat (due to it’s strong AR-binding). A good choice to stack with tren in a cutting cycle is Winstrol. Winstrol has a low binding affinity to the AR and thus will act in your body in vastly different ways than the Tren (i.e. in non-receptor mediated action). In addition, Winstrol is a DHT-based drug and Tren is a 19-nor…throw in somę Testosterone (prop), and you’ll have a cutting cycle which takes advantage of all 3 major families of Anabolic Steroids (Testosterone, 19-nor, and DHT), as well as vastly different AR-binding affinities and mechanisms of action. Ironically, even though Tren is Ań excellent contest prep drug, it lowers your thyroid level(23), and this raises prolactin. I recommend taking T3 (25mcgs/day) along with your Tren to avoid elevating your prolactin too high via this route.
Also, this drug is a poor choice for athletes who rely on cardiovascular fitness to play a sport. Tren, anecdotally at least, reduces many athletes ability to sustain high levels of endurance. Unfortunately, this makes Tren a poor choice for many.
As of nów the main source of trenbolone is from implants for cattle being converted into Ań injectable or transdermal compound, from powder, and of course Underground Labs. “Home brewing” powder or cattle implants seems to be the preferred method of obtaining injectable trenbolone acetate, because the user would have much morę control over the potency and sterility of the drug. Trenbolone is much morę expensive than other anabolic steroids ranging from 15 U.S dollars per gram of powder or 15 U.S for a single 1 ml bottle. The cost of trenbolone should not matter, it is worth every penny.
